TY - JOUR
T1 - Mononuclear Cell Magnesium content remains unchanged in various hypertensive disorders of pregnancy
AU - Frenkel, Yair
AU - Weiss, M.
AU - Shefi, M.
AU - Lusky, A.
AU - Mashiach, S.
AU - Dolev, E.
PY - 1994
Y1 - 1994
N2 - Serum magnesium levels, as well as magnesium content of red blood cells and peripheral mononuclear cells, were examined in 31 pregnant women in their third trimester. Ten were preeclamptic; chronic hypertension was found in 10, and 11 were normotensive. Magnesium serum levels were 1.2 ± 0.1, 1.2 ± 0.1 and 1.3 ± 0.1 mEq/1 in the normotensives, chronic hypertensives and preeclamptics, respectively. Red blood cell magnesium concentration was 3.4 ± 0.4, 3.7 ± 0.7 and 3.5 ± 0.5 mEq/1, and mononuclear magnesium content was 37.9 ± 30.6, 27.6 ± 15.9 and 30.2 ± 25.7 fg/cell in the same groups, respectively. These changes were not statistically significant. The results do not support the hypothesis that magnesium deficiency is involved in the pathophysiology of preeclampsia.
AB - Serum magnesium levels, as well as magnesium content of red blood cells and peripheral mononuclear cells, were examined in 31 pregnant women in their third trimester. Ten were preeclamptic; chronic hypertension was found in 10, and 11 were normotensive. Magnesium serum levels were 1.2 ± 0.1, 1.2 ± 0.1 and 1.3 ± 0.1 mEq/1 in the normotensives, chronic hypertensives and preeclamptics, respectively. Red blood cell magnesium concentration was 3.4 ± 0.4, 3.7 ± 0.7 and 3.5 ± 0.5 mEq/1, and mononuclear magnesium content was 37.9 ± 30.6, 27.6 ± 15.9 and 30.2 ± 25.7 fg/cell in the same groups, respectively. These changes were not statistically significant. The results do not support the hypothesis that magnesium deficiency is involved in the pathophysiology of preeclampsia.
KW - Chronic hypertension
KW - Intracellular magnesium
KW - Preeclampsia
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=0028126794&partnerID=8YFLogxK
U2 - 10.1159/000292485
DO - 10.1159/000292485
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AN - SCOPUS:0028126794
SN - 0378-7346
VL - 38
SP - 220
EP - 222
JO - Gynecologic and Obstetric Investigation
JF - Gynecologic and Obstetric Investigation
IS - 4
ER -