Mononuclear Cell Magnesium content remains unchanged in various hypertensive disorders of pregnancy

Yair Frenkel; M. Weiss; M. Shefi; A. Lusky; S. Mashiach; E. Dolev

doi:10.1159/000292485

Mononuclear Cell Magnesium content remains unchanged in various hypertensive disorders of pregnancy

Yair Frenkel^*, M. Weiss, M. Shefi, A. Lusky, S. Mashiach, E. Dolev

^*Corresponding author for this work

Clinical Departments

Research output: Contribution to journal › Article › peer-review

Abstract

Serum magnesium levels, as well as magnesium content of red blood cells and peripheral mononuclear cells, were examined in 31 pregnant women in their third trimester. Ten were preeclamptic; chronic hypertension was found in 10, and 11 were normotensive. Magnesium serum levels were 1.2 ± 0.1, 1.2 ± 0.1 and 1.3 ± 0.1 mEq/1 in the normotensives, chronic hypertensives and preeclamptics, respectively. Red blood cell magnesium concentration was 3.4 ± 0.4, 3.7 ± 0.7 and 3.5 ± 0.5 mEq/1, and mononuclear magnesium content was 37.9 ± 30.6, 27.6 ± 15.9 and 30.2 ± 25.7 fg/cell in the same groups, respectively. These changes were not statistically significant. The results do not support the hypothesis that magnesium deficiency is involved in the pathophysiology of preeclampsia.

Original language	English
Pages (from-to)	220-222
Number of pages	3
Journal	Gynecologic and Obstetric Investigation
Volume	38
Issue number	4
DOIs	https://doi.org/10.1159/000292485
State	Published - 1994

Keywords

Chronic hypertension
Intracellular magnesium
Preeclampsia
Pregnancy

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10.1159/000292485

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@article{57c20374119040d8b52129044f1d6e85,

title = "Mononuclear Cell Magnesium content remains unchanged in various hypertensive disorders of pregnancy",

abstract = "Serum magnesium levels, as well as magnesium content of red blood cells and peripheral mononuclear cells, were examined in 31 pregnant women in their third trimester. Ten were preeclamptic; chronic hypertension was found in 10, and 11 were normotensive. Magnesium serum levels were 1.2 ± 0.1, 1.2 ± 0.1 and 1.3 ± 0.1 mEq/1 in the normotensives, chronic hypertensives and preeclamptics, respectively. Red blood cell magnesium concentration was 3.4 ± 0.4, 3.7 ± 0.7 and 3.5 ± 0.5 mEq/1, and mononuclear magnesium content was 37.9 ± 30.6, 27.6 ± 15.9 and 30.2 ± 25.7 fg/cell in the same groups, respectively. These changes were not statistically significant. The results do not support the hypothesis that magnesium deficiency is involved in the pathophysiology of preeclampsia.",

keywords = "Chronic hypertension, Intracellular magnesium, Preeclampsia, Pregnancy",

author = "Yair Frenkel and M. Weiss and M. Shefi and A. Lusky and S. Mashiach and E. Dolev",

year = "1994",

doi = "10.1159/000292485",

language = "אנגלית",

volume = "38",

pages = "220--222",

journal = "Gynecologic and Obstetric Investigation",

issn = "0378-7346",

publisher = "S. Karger AG",

number = "4",

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T1 - Mononuclear Cell Magnesium content remains unchanged in various hypertensive disorders of pregnancy

AU - Frenkel, Yair

AU - Weiss, M.

AU - Shefi, M.

AU - Lusky, A.

AU - Mashiach, S.

AU - Dolev, E.

PY - 1994

Y1 - 1994

N2 - Serum magnesium levels, as well as magnesium content of red blood cells and peripheral mononuclear cells, were examined in 31 pregnant women in their third trimester. Ten were preeclamptic; chronic hypertension was found in 10, and 11 were normotensive. Magnesium serum levels were 1.2 ± 0.1, 1.2 ± 0.1 and 1.3 ± 0.1 mEq/1 in the normotensives, chronic hypertensives and preeclamptics, respectively. Red blood cell magnesium concentration was 3.4 ± 0.4, 3.7 ± 0.7 and 3.5 ± 0.5 mEq/1, and mononuclear magnesium content was 37.9 ± 30.6, 27.6 ± 15.9 and 30.2 ± 25.7 fg/cell in the same groups, respectively. These changes were not statistically significant. The results do not support the hypothesis that magnesium deficiency is involved in the pathophysiology of preeclampsia.

AB - Serum magnesium levels, as well as magnesium content of red blood cells and peripheral mononuclear cells, were examined in 31 pregnant women in their third trimester. Ten were preeclamptic; chronic hypertension was found in 10, and 11 were normotensive. Magnesium serum levels were 1.2 ± 0.1, 1.2 ± 0.1 and 1.3 ± 0.1 mEq/1 in the normotensives, chronic hypertensives and preeclamptics, respectively. Red blood cell magnesium concentration was 3.4 ± 0.4, 3.7 ± 0.7 and 3.5 ± 0.5 mEq/1, and mononuclear magnesium content was 37.9 ± 30.6, 27.6 ± 15.9 and 30.2 ± 25.7 fg/cell in the same groups, respectively. These changes were not statistically significant. The results do not support the hypothesis that magnesium deficiency is involved in the pathophysiology of preeclampsia.

KW - Chronic hypertension

KW - Intracellular magnesium

KW - Preeclampsia

KW - Pregnancy

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SN - 0378-7346

VL - 38

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EP - 222

JO - Gynecologic and Obstetric Investigation

JF - Gynecologic and Obstetric Investigation

IS - 4

ER -

Mononuclear Cell Magnesium content remains unchanged in various hypertensive disorders of pregnancy

Abstract

Keywords

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