Mononuclear Cell Magnesium content remains unchanged in various hypertensive disorders of pregnancy

Yair Frenkel*, M. Weiss, M. Shefi, A. Lusky, S. Mashiach, E. Dolev

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Serum magnesium levels, as well as magnesium content of red blood cells and peripheral mononuclear cells, were examined in 31 pregnant women in their third trimester. Ten were preeclamptic; chronic hypertension was found in 10, and 11 were normotensive. Magnesium serum levels were 1.2 ± 0.1, 1.2 ± 0.1 and 1.3 ± 0.1 mEq/1 in the normotensives, chronic hypertensives and preeclamptics, respectively. Red blood cell magnesium concentration was 3.4 ± 0.4, 3.7 ± 0.7 and 3.5 ± 0.5 mEq/1, and mononuclear magnesium content was 37.9 ± 30.6, 27.6 ± 15.9 and 30.2 ± 25.7 fg/cell in the same groups, respectively. These changes were not statistically significant. The results do not support the hypothesis that magnesium deficiency is involved in the pathophysiology of preeclampsia.

Original languageEnglish
Pages (from-to)220-222
Number of pages3
JournalGynecologic and Obstetric Investigation
Volume38
Issue number4
DOIs
StatePublished - 1994

Keywords

  • Chronic hypertension
  • Intracellular magnesium
  • Preeclampsia
  • Pregnancy

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