Monoclonal antibodies to red cell cytoskeletal proteins

Britta Hardy*, Jerome M. Loew, Inga Melchers, Dominique Charron, Stanley L. Schrier

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Monoclonal antibodies to human red cell cytoskeletal proteins were produced following immunization of mice with Triton shells produced from intact red cells. Two lines producing antibodies binding to spectrin and actin, respectively, were subcloned and further characterized. Clones producing the anti-spectrin antibody were stable. The antibody was monoclonal and specific for spectrin band 2. The anti-actin clones were unstable.

Original languageEnglish
Pages (from-to)334-337
Number of pages4
JournalArchives of Biochemistry and Biophysics
Issue number1
StatePublished - Jan 1982
Externally publishedYes


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