TY - JOUR
T1 - Moloney Lymphoma Antibodies from Mice; Localization in Spleens of Moloney Lymphoma Bearing Mice
AU - Witz, Isaac
AU - Klein, George
AU - Pressman, David
N1 - Funding Information:
Supported in part by Contract No. AT-(30-1)-2651 from the United States Atomic Energy Commission, by Grant No. DRG 598 from the Damon Runyon Memorial Fund and by the Swedish Cancer Society.
PY - 1969/4
Y1 - 1969/4
N2 - Radioiodine labeled globulin isolated from isogeneic mice immunized with irradiated Moloney lymphoma cells, and purified by absorption on the elution from the insoluble sediment of a homogenate of the Moloney lymphoma were shown to localize in spleen of Moloney lymphoma-bearing mice. Three different Moloney lymphomas were tested. In all three of them, there was a significant increase in specific localization of the antiserum globulin in spleen of the lymphoma-bearing mice, as compared to normal mice. There was little localization in the tumors however. The tests were done utilizing the paired-labeled antibody technic.
AB - Radioiodine labeled globulin isolated from isogeneic mice immunized with irradiated Moloney lymphoma cells, and purified by absorption on the elution from the insoluble sediment of a homogenate of the Moloney lymphoma were shown to localize in spleen of Moloney lymphoma-bearing mice. Three different Moloney lymphomas were tested. In all three of them, there was a significant increase in specific localization of the antiserum globulin in spleen of the lymphoma-bearing mice, as compared to normal mice. There was little localization in the tumors however. The tests were done utilizing the paired-labeled antibody technic.
UR - http://www.scopus.com/inward/record.url?scp=0014495018&partnerID=8YFLogxK
U2 - 10.3181/00379727-130-33728
DO - 10.3181/00379727-130-33728
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AN - SCOPUS:0014495018
SN - 0037-9727
VL - 130
SP - 1102
EP - 1105
JO - Experimental Biology and Medicine
JF - Experimental Biology and Medicine
IS - 4
ER -
