Molekuliarnoe klonirovanie genov plazmidy ColIb-P9, otvetstvennykh za ee mutatornuiu funktsiiu.

Translated title of the contribution: Molecular cloning of plasmid ColIb-P9 genes responsible for its mutator function

M. N. Kolot, I. A. Khmel'

Research output: Contribution to journalArticlepeer-review

Abstract

The localization of plasmid ColIb-P9 muc genes mediating the plasmids protective and mutagenesis-increasing activity has been determined. The increase of muc genes dose by cloning them within the multicopy vector has been shown to repress the mutator function of the plasmid. No essential homology has been revealed between ColIb-P9 muc gene nucleotide sequences, pKM101 muc genes with a similar function, and umuDC chromosome genes. It has been shown that the synthesis of 38 KD protein is essential for the manifestation of the mutator function of the plasmid.

Translated title of the contributionMolecular cloning of plasmid ColIb-P9 genes responsible for its mutator function
Original languageRussian
Pages (from-to)8-14
Number of pages7
JournalMolekuliarnaia genetika, mikrobiologiia i virusologiia
Issue number9
StatePublished - Sep 1988

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