Abstract
Systemic lupus erythematosus is a multi-systemic autoimmune disease distinguished by the presence of various autoantibodies. Like most autoimmune diseases, systemic lupus erythematosus is believed to be induced by a combination of genetic, immunologic, and environmental factors, mainly infectious agents. Molecular mimicry between an infectious antigen and self-components is implicated as a pivotal mechanism by which autoimmune diseases such as systemic lupus erythematosus are triggered. Here we review the current evidence of molecular mimicry between different infectious agents and systemic lupus erythematosus.
| Original language | English |
|---|---|
| Pages (from-to) | 1181-1185 |
| Number of pages | 5 |
| Journal | Lupus |
| Volume | 18 |
| Issue number | 13 |
| DOIs | |
| State | Published - 2009 |
Keywords
- Autoantibodies
- Autoimmunity
- Cross-reactivity
- Epstein-Barr virus
- Infections
- Molecular mimicry
- Systemic lupus erythematosus