Molar-incisor hypomineralization: Positive correlation with atopic dermatitis and food allergies

Aim: Molar-incisor hypomineralization is a disturbance in dental development that involves first permanent molars as well as permanent incisors with a prevalence that ranges from 2.5% to 40%. The objective of this study was to investigate the etiology of molar-incisor hypomineralization among school children from two randomly selected towns in the province of Barcelona, Spain. Study design: A cross-sectional study was conducted with 705 children ranging in age from six years-old to 14 years and 11 months-old. Full mouth examinations were carried out in accordance with the European Academy of Paediatric Dentistry criteria for the diagnosis of molar-incisor hypomineralization, from April to July 2016. Results: A total of 56 cases of molar-incisor hypomineralization were found in 22 (39.3%) boys and 34 (60.7%) girls. MIH was significantly more prevalent among those who had atopic dermatitis (OR=90.9; 33.4-247.1 CI 95%), food allergies (OR=104.2; 12.2-887.5 CI 95%), bronchitis/asthma (OR=5.3; 2.7-10.1 CI 95%), varicella (OR=96.3; 41.9-221.1 CI 95%), otitis media (OR=12.2; 6.3-23.5 CI 95%), pneumonia (OR=276.7; 35.1-2183.7 CI 95%), and febrile syndrome (OR=7.8; 4.1-14.8 CI 95%). Conclusions: The present research reveals for the first time a statistically significant relationship between atopic dermatitis and food allergies with the presence of molar-incisor hypomineralization.