Modifier theory of meiotic drive: Is Mendelian segregation stable?

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The evolutionary fate of rare modifiers, based on the modifier theory of meiotic drive, is studied in this paper. It is shown that a polymorphism based on Mendelian segregation is never stable for any recombination frequencies between 0 and 1 2, and that, for tight linkage between the main locus and the modifier locus, the modifier locus tends towards heterozygosity.

Original languageEnglish
Pages (from-to)127-132
Number of pages6
JournalTheoretical Population Biology
Issue number2
StatePublished - Oct 1976


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