Mitogen activated protein kinases (MAPKs) as regulators of spermatogenesis and spermatozoa functions

Tal Almog, Zvi Naor*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

90 Scopus citations

Abstract

Spermatogenesis, culminating in the generation of mature motile spermatozoa, is a complex biological process that is regulated by cytokines and hormones of the male reproductive system. Spermatozoa must first undergo a series of biochemical processes termed capacitation, which is followed by acrosome reaction and egg fertilization. Here we review the role of mitogen-activated protein kinases (MAPK) cascades in spermatogenesis and spermatozoa functions.

Original languageEnglish
Pages (from-to)39-44
Number of pages6
JournalMolecular and Cellular Endocrinology
Volume282
Issue number1-2
DOIs
StatePublished - 30 Jan 2008

Funding

FundersFunder number
NOFAR
UNDP/UNFPA/WHO
World Bank Group
World Health OrganizationA15118
Ministerio de Ciencia y Tecnología

    Keywords

    • ERK
    • MAPK
    • Spermatogenesis
    • Spermatozoa

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