MiRNAs and lncRNAs as biomarkers of toxicant exposure

Ronit Machtinger, Valentina Bollati, Andrea A. Baccarelli

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Different environmental exposures such as chemicals, metals, or particles may negatively affect animal and human health. These materials can alter the normal function of the endocrine system or exert toxicity specifically on the nervous, hematopoietic, respiratory, or digestive systems. However, the mechanisms of action remain largely unexplored. Recent data suggest that environmental exposures can lead to adverse health effects by altering expression of noncoding RNA, including microRNA and long noncoding RNA. This chapter reviews the current literature on the roles of noncoding RNAs as part of the mechanisms of action of environmental exposures.

Original languageEnglish
Title of host publicationToxicoepigenetics
Subtitle of host publicationCore Principles and Applications
Number of pages11
ISBN (Electronic)9780128124338
ISBN (Print)9780128124345
StatePublished - 1 Jan 2018


  • Bisphenol a
  • Endocrine disruptor chemicals
  • Long noncoding rna
  • Mirna
  • Noncoding rnas
  • Particles
  • Phthalates


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