MiRNAs and lncRNAs as biomarkers of toxicant exposure

Ronit Machtinger, Valentina Bollati, Andrea A. Baccarelli

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

4 Scopus citations

Abstract

Different environmental exposures such as chemicals, metals, or particles may negatively affect animal and human health. These materials can alter the normal function of the endocrine system or exert toxicity specifically on the nervous, hematopoietic, respiratory, or digestive systems. However, the mechanisms of action remain largely unexplored. Recent data suggest that environmental exposures can lead to adverse health effects by altering expression of noncoding RNA, including microRNA and long noncoding RNA. This chapter reviews the current literature on the roles of noncoding RNAs as part of the mechanisms of action of environmental exposures.

Original languageEnglish
Title of host publicationToxicoepigenetics
Subtitle of host publicationCore Principles and Applications
PublisherElsevier
Pages237-247
Number of pages11
ISBN (Electronic)9780128124338
ISBN (Print)9780128124345
DOIs
StatePublished - 1 Jan 2018

Keywords

  • Bisphenol a
  • Endocrine disruptor chemicals
  • Long noncoding rna
  • Mirna
  • Noncoding rnas
  • Particles
  • Phthalates

Fingerprint

Dive into the research topics of 'MiRNAs and lncRNAs as biomarkers of toxicant exposure'. Together they form a unique fingerprint.

Cite this