Mirabimides A-D, new N-acylpyrrolinones from the blue-green alga Scytonema mirabile

Shmuel Carmeli*, Richard E. Moore, Gregory M.L. Patterson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

Mirabimide A, the major imide from the terrestrial blue-green alga Scytonema mirabile (Dillwyn) Bornet (strain BY-8-1), is N-[2-(N,N-dimethylleucyl)oxy-3-methylpentanoyl-N-methylvalyl-prolyl]-4-methoxy-5-isopropyl-3-pyrrolin-2-one. Mirabimides B-D are the valyl, 2-oxy-3-methylbutanoyl, and N-acetyl-N-methylleucyl analogs, respectively. The absolute configurations of the five asymmetric carbons in the mirabimides are proposed to be all S, but the assignments for the dimethylleucine units in A-C and the hydroxyacid units in B-D are tentative.

Original languageEnglish
Pages (from-to)2087-2096
Number of pages10
JournalTetrahedron
Volume47
Issue number12-13
DOIs
StatePublished - 1991
Externally publishedYes

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