Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor-positive desmoid tumor

A. Halevy; I. Samuk; Z. Halpern; L. Copel; J. Sandbank; Y. Ziv

doi:10.1007/s10151-010-0591-2

Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor-positive desmoid tumor

A. Halevy^*, I. Samuk, Z. Halpern, L. Copel, J. Sandbank, Y. Ziv

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

We report the case of a patient who developed a desmoid tumor following total proctocolectomy and J-pouch reconstruction that was unresponsive to any medical treatment. Based on estrogen receptor alpha (ERα) and progesterone receptor (PR) evaluation (ERα-negative, but PR-positive), treatment with mifepristone, a pure antiprogesterone drug, was initiated, and partial tumor regression was achieved.

Original language	English
Pages (from-to)	265-267
Number of pages	3
Journal	Techniques in Coloproctology
Volume	14
Issue number	3
DOIs	https://doi.org/10.1007/s10151-010-0591-2
State	Published - Sep 2010
Externally published	Yes

Keywords

Desmoid tumor
Hormonal receptor
Mifepristone

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10.1007/s10151-010-0591-2

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author = "A. Halevy and I. Samuk and Z. Halpern and L. Copel and J. Sandbank and Y. Ziv",

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AU - Copel, L.

AU - Sandbank, J.

AU - Ziv, Y.

PY - 2010/9

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KW - Hormonal receptor

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Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor-positive desmoid tumor

Abstract

Keywords

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