Abstract
Objective: To study the association between midtrimester triple-test levels and renal function in pregnant women with chronic hypertension. Methods: Forty-three patients with chronic hypertension for whom renal function was evaluated by the creatinine clearance test between 14- and 20-weeks gestation were studied. Midtrimester triple-test values obtained as part of Down screening program were correlated with renal function. Results hCG correlated inversely with creatinine clearance (r = -0.345; p = 0.002) and directly with alpha-fetoprotein (r = 0.499; p = 0.003). Conclusions: In pregnant women with chronic hypertension, impaired renal function may alter midtrimester maternal serum hCG levels.
Original language | English |
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Pages (from-to) | 166-167 |
Number of pages | 2 |
Journal | Prenatal Diagnosis |
Volume | 23 |
Issue number | 2 |
DOIs | |
State | Published - 1 Feb 2003 |
Externally published | Yes |
Keywords
- Chronic hypertension
- Midtrimester triple test
- Renal function