Midazolam in treatment of epileptic seizures

Eli Lahat*, Mordelhai Aladjem, Gideon Eshel, Tzvy Bistritzer, Yitzchak Katz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Midazolam (Versed®), the first water-soluble benzodiazepine, has had widespread acceptance as a parenteral anxiolitic agent. Its antiepileptic properties were studied in adult patients with good results. Midazolam was administered intramuscularly to 48 children, ages 4 months to 14 years, with 69 epileptic episodes of various types. In all but 5 epileptic episodes, seizures stopped 1-10 min after injection. These results suggest that midazolam administered intramuscularly may be useful in a variety of epileptic seizures during childhood, specifically when attempts to introduce an intravenous line in convulsing children are unsuccessful.

Original languageEnglish
Pages (from-to)215-216
Number of pages2
JournalPediatric Neurology
Issue number3
StatePublished - 1992


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