Midazolam in treatment of epileptic seizures

Eli Lahat; Mordelhai Aladjem; Gideon Eshel; Tzvy Bistritzer; Yitzchak Katz

doi:10.1016/0887-8994(92)90071-6

Midazolam in treatment of epileptic seizures

Eli Lahat, Mordelhai Aladjem, Gideon Eshel, Tzvy Bistritzer, Yitzchak Katz

Clinical Departments

Research output: Contribution to journal › Article › peer-review

Abstract

Midazolam (Versed®), the first water-soluble benzodiazepine, has had widespread acceptance as a parenteral anxiolitic agent. Its antiepileptic properties were studied in adult patients with good results. Midazolam was administered intramuscularly to 48 children, ages 4 months to 14 years, with 69 epileptic episodes of various types. In all but 5 epileptic episodes, seizures stopped 1-10 min after injection. These results suggest that midazolam administered intramuscularly may be useful in a variety of epileptic seizures during childhood, specifically when attempts to introduce an intravenous line in convulsing children are unsuccessful.

Original language	English
Pages (from-to)	215-216
Number of pages	2
Journal	Pediatric Neurology
Volume	8
Issue number	3
DOIs	https://doi.org/10.1016/0887-8994(92)90071-6
State	Published - 1992

Access to Document

10.1016/0887-8994(92)90071-6

Cite this

@article{82ac42125cdf4336a0e5c29ff6d9df29,

title = "Midazolam in treatment of epileptic seizures",

abstract = "Midazolam (Versed{\textregistered}), the first water-soluble benzodiazepine, has had widespread acceptance as a parenteral anxiolitic agent. Its antiepileptic properties were studied in adult patients with good results. Midazolam was administered intramuscularly to 48 children, ages 4 months to 14 years, with 69 epileptic episodes of various types. In all but 5 epileptic episodes, seizures stopped 1-10 min after injection. These results suggest that midazolam administered intramuscularly may be useful in a variety of epileptic seizures during childhood, specifically when attempts to introduce an intravenous line in convulsing children are unsuccessful.",

author = "Eli Lahat and Mordelhai Aladjem and Gideon Eshel and Tzvy Bistritzer and Yitzchak Katz",

year = "1992",

doi = "10.1016/0887-8994(92)90071-6",

language = "אנגלית",

volume = "8",

pages = "215--216",

journal = "Pediatric Neurology",

issn = "0887-8994",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Midazolam in treatment of epileptic seizures

AU - Lahat, Eli

AU - Aladjem, Mordelhai

AU - Eshel, Gideon

AU - Bistritzer, Tzvy

AU - Katz, Yitzchak

PY - 1992

Y1 - 1992

N2 - Midazolam (Versed®), the first water-soluble benzodiazepine, has had widespread acceptance as a parenteral anxiolitic agent. Its antiepileptic properties were studied in adult patients with good results. Midazolam was administered intramuscularly to 48 children, ages 4 months to 14 years, with 69 epileptic episodes of various types. In all but 5 epileptic episodes, seizures stopped 1-10 min after injection. These results suggest that midazolam administered intramuscularly may be useful in a variety of epileptic seizures during childhood, specifically when attempts to introduce an intravenous line in convulsing children are unsuccessful.

AB - Midazolam (Versed®), the first water-soluble benzodiazepine, has had widespread acceptance as a parenteral anxiolitic agent. Its antiepileptic properties were studied in adult patients with good results. Midazolam was administered intramuscularly to 48 children, ages 4 months to 14 years, with 69 epileptic episodes of various types. In all but 5 epileptic episodes, seizures stopped 1-10 min after injection. These results suggest that midazolam administered intramuscularly may be useful in a variety of epileptic seizures during childhood, specifically when attempts to introduce an intravenous line in convulsing children are unsuccessful.

UR - http://www.scopus.com/inward/record.url?scp=0026636869&partnerID=8YFLogxK

U2 - 10.1016/0887-8994(92)90071-6

DO - 10.1016/0887-8994(92)90071-6

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

AN - SCOPUS:0026636869

VL - 8

SP - 215

EP - 216

JO - Pediatric Neurology

JF - Pediatric Neurology

SN - 0887-8994

IS - 3

ER -

Midazolam in treatment of epileptic seizures

Abstract

Access to Document

Other files and links

Fingerprint

Cite this