Microevolution and patterns of transmission of shigella sonnei within cyclic outbreaks of shigellosis, Israel

Adi Behar*, Kate Susan Baker, Ravit Bassal, Analia Ezernitchi, Lea Valinsky, Nicholas R. Thomson, Daniel Cohen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Whole-genome sequencing unveiled host and environment-related insights to Shigella sonnei transmission within cyclic epidemics during 2000–2012 in Israel. The Israeli reservoir contains isolates belonging to S. sonnei lineage III but of different origin, shows loss of tetracycline resistance genes, and little genetic variation within the O antigen: highly relevant for Shigella vaccine development.

Original languageEnglish
Pages (from-to)1335-1339
Number of pages5
JournalEmerging Infectious Diseases
Volume24
Issue number7
DOIs
StatePublished - Jul 2018

Funding

FundersFunder number
European Union Seventh Frame-work Programme
Wellcome Trust098051
Seventh Framework Programme261472
Seventh Framework Programme

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