Microcystbiopterins A-E, five O-methylated biopterin glycosides from two Microcystis spp. bloom biomasses

Marina Lifshits, Dimitri Kovalerchik, Shmuel Carmeli*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Five previously undescribed biopterin glycosides, microcystbiopterin A-E, were isolated from the extracts of two bloom materials of Microcystis spp. collected from a fishpond (IL-337) and Lake Kinneret (IL-347), Israel. The structure of the pterins was established by interpretation of their UV, CD, 1D and 2D NMR spectra and HR mass measurements. Microcystbiopterin D is the first heptose containing pterin glycoside to be reported in the literature. Their antimicrobial and cytotoxic properties were evaluated but all were found not active in both assays.

Original languageEnglish
Pages (from-to)69-74
Number of pages6
JournalPhytochemistry
Volume123
DOIs
StatePublished - 1 Mar 2016

Funding

FundersFunder number
Israel Science Foundation776/06, 037/02

    Keywords

    • Biopterin glycosides
    • Cyanobacteria
    • Microcystbiopterins A-E
    • Microcystis spp. (Microcystaceae)
    • UV-A

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