TY - JOUR
T1 - Methyl-CpG-binding domain proteins in plants
T2 - interpreters of DNA methylation
AU - Zemach, Assaf
AU - Grafi, Gideon
N1 - Funding Information:
We thank Yigal Avivi for critical reading and editing of the manuscript. A.Z. is a recipient of the Israeli Ministry of Science Eshkol Fellowship for PhD students. Our research was supported by the Israel Science Foundation and by The Jewish Colonization Association (ICA).
PY - 2007/2
Y1 - 2007/2
N2 - The effect of DNA methylation on various aspects of plant cellular and developmental processes has been well documented over the past 35 years. However, the underlying molecular mechanism interpreting the methylation signal has only recently been explored with the isolation and characterization of the Arabidopsis methyl-CpG-binding domain (MBD) proteins. In this review, we highlight recent advances and present new models concerning Arabidopsis MBD proteins and their possible role in controlling chromatin structure mediated by CpG methylation.
AB - The effect of DNA methylation on various aspects of plant cellular and developmental processes has been well documented over the past 35 years. However, the underlying molecular mechanism interpreting the methylation signal has only recently been explored with the isolation and characterization of the Arabidopsis methyl-CpG-binding domain (MBD) proteins. In this review, we highlight recent advances and present new models concerning Arabidopsis MBD proteins and their possible role in controlling chromatin structure mediated by CpG methylation.
UR - http://www.scopus.com/inward/record.url?scp=33846900215&partnerID=8YFLogxK
U2 - 10.1016/j.tplants.2006.12.004
DO - 10.1016/j.tplants.2006.12.004
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C2 - 17208509
AN - SCOPUS:33846900215
SN - 1360-1385
VL - 12
SP - 80
EP - 85
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 2
ER -