Methyl-CpG-binding domain proteins in plants: interpreters of DNA methylation

Assaf Zemach, Gideon Grafi

Research output: Contribution to journalReview articlepeer-review


The effect of DNA methylation on various aspects of plant cellular and developmental processes has been well documented over the past 35 years. However, the underlying molecular mechanism interpreting the methylation signal has only recently been explored with the isolation and characterization of the Arabidopsis methyl-CpG-binding domain (MBD) proteins. In this review, we highlight recent advances and present new models concerning Arabidopsis MBD proteins and their possible role in controlling chromatin structure mediated by CpG methylation.

Original languageEnglish
Pages (from-to)80-85
Number of pages6
JournalTrends in Plant Science
Issue number2
StatePublished - Feb 2007
Externally publishedYes


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