Methodologies and Challenges for CRISPR/Cas9 Mediated Genome Editing of the Mammalian Brain

Keyphrases

• Cas9 Protein 100%
• Genome Editing 100%
• Mammalian Brain 100%
• Recent Advances 20%
• Molecular Mechanism 20%
• Cell Behavior 20%
• Transgenic Mouse Model 20%
• Large Distances 20%
• Protein Signaling 20%
• Cellular Level 20%
• Glia 20%
• CRISPR-Cas9 System 20%
• Signaling Complex 20%
• Intracellular Compartments 20%
• Synapse Function 20%
• Neuronal Population 20%
• Polarized Cells 20%
• Endogenous Protein 20%
• Whole Animal 20%
• Gene Editing 20%
• Fertilized Egg 20%
• Subcellular Structure 20%
• Circuit Function 20%

Neuroscience

• CRISPR 100%
• Synapse 33%
• Protein 33%
• Glia 33%