Metastatic trophoblastic disease following partial hydatidiform mole: Case report and literature review

Joseph Menczer, Ofer Girtler, Liliana Zajdel, Marek Glezerman

Research output: Contribution to journalArticlepeer-review

Abstract

A patient with a triploid partial hydatidiform who had lung metastasis is presented. Complete response was achieved with methotrexate chemotherapy. A review of the literature revealed only 11 previously reported cases. In many of them clinical data are missing. All had lung metastasis and 1 had in addition a metastasis in the vagina. Only 1 of these patients died of disease. The others responded well to chemotherapy. Metastatic trophoblastic disease following partial mole is very rare but the exact prevalence is not known. Since risk factors for developing metastatic trophoblastic disease subsequent to partial mole are not known, all patients should be followed.

Original languageEnglish
Pages (from-to)304-307
Number of pages4
JournalGynecologic Oncology
Volume74
Issue number2
DOIs
StatePublished - Aug 1999
Externally publishedYes

Keywords

  • Metastatic trophoblastic disease
  • Methotrexate chemotherapy
  • Partial mole

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