@inbook{a4dc7719c03a446ca91ee90407b23f3c,
title = "Metabolomic Analysis of Natural Variation in Arabidopsis",
abstract = "Methodological advances in coupled-mass spectrometry (gas chromatography and liquid chromatography; GC-MS and LC-MS) have rendered the profiling of highly complex plant extracts relatively facile and allowed that their high-throughput use aids the investigation of a range of biological questions. Among these is the elucidation of the genetic factors underlying metabolite abundance. For this purpose genome-wide association studies (GWAS) are being widely adopted in Arabidopsis with the resultant quantitative trait loci being subjected to cross-validation by the use of recombinant inbred lines, introgression lines, and T-DNA insertional knockout lines.",
keywords = "Gas-chromatography mass-spectrometry, Genome-wide association mapping, Liquid-chromatography mass-spectrometry, Metabolomics, QTL analysis",
author = "Si Wu and Saleh Alseekh and Yariv Brotman and Fernie, {Alisdair R.}",
note = "Publisher Copyright: {\textcopyright} 2021, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2021",
doi = "10.1007/978-1-0716-0880-7_19",
language = "אנגלית",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "393--411",
booktitle = "Methods in Molecular Biology",
}