Meso-Methylhydroxy BODIPY: A scaffold for photo-labile protecting groups

Naama Rubinstein; Pei Liu; Evan W. Miller; Roy Weinstain

doi:10.1039/c5cc00550g

Meso-Methylhydroxy BODIPY: A scaffold for photo-labile protecting groups

Naama Rubinstein, Pei Liu, Evan W. Miller, Roy Weinstain^*

^*Corresponding author for this work

School of Plant Sciences and Food Security

Research output: Contribution to journal › Article › peer-review

Abstract

Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.

Original language	English
Pages (from-to)	6369-6372
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	29
DOIs	https://doi.org/10.1039/c5cc00550g
State	Published - 14 Apr 2015

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abstract = "Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.",

author = "Naama Rubinstein and Pei Liu and Miller, {Evan W.} and Roy Weinstain",

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AU - Rubinstein, Naama

AU - Liu, Pei

AU - Miller, Evan W.

AU - Weinstain, Roy

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

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Y1 - 2015/4/14

N2 - Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.

AB - Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.

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Meso-Methylhydroxy BODIPY: A scaffold for photo-labile protecting groups

Abstract

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