Membrane hemifusion: Crossing a chasm in two leaps

Leonid V. Chernomordik*, Michael M. Kozlov

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

During membrane fusion, the outer leaflets of the two membranes merge first, whereas the distal membrane leaflets remain separate until the opening of a fusion pore. This intermediate stage, called hemifusion, is a critical event shared by exocytosis, protein trafficking, and viral entry.

Original languageEnglish
Pages (from-to)375-382
Number of pages8
JournalCell
Volume123
Issue number3
DOIs
StatePublished - 4 Nov 2005

Funding

FundersFunder number
USA-Israel Science Foundation
National Institutes of Health
National Institute of Child Health and Human Development
Bloom's Syndrome Foundation
Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentZ01HD001501
Marie Curie
Israel Science Foundation

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