Membrane Curvature in Synaptic Vesicle Fusion and Beyond

Harvey T. McMahon*, Michael M. Kozlov, Sascha Martens

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


Recent evidence suggests that the Ca2+-sensors synaptotagmin-1 and Doc2b deform synaptic membranes during synaptic vesicle exocytosis. We discuss how local curvature generated by these and other proteins may stimulate membrane fusion and discuss the potential implications of these findings for other cellular fusion events.

Original languageEnglish
Pages (from-to)601-605
Number of pages5
Issue number5
StatePublished - 5 Mar 2010


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