Mechanisms of Leukemia Evolution: Lessons from a Congenital Syndrome

Yehudit Birger, Ruth Shiloh, Shai Izraeli*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


Studies of the mechanisms of acute leukemia transformation from a preleukemic state in humans are hampered by the absence of clinical preleukemia syndromes. In this issue of Cancer Cell, Labuhn et al. provide a functional genomics view on the leukemic evolution from congenital preleukemia in children with Down syndrome.

Original languageEnglish
Pages (from-to)115-117
Number of pages3
JournalCancer Cell
Issue number2
StatePublished - 12 Aug 2019


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