Mechanical, physical and biological characterization of soy protein films loaded with bupivacaine for wound healing applications

Daniella Goder, Lior Matsliah, Shir Giladi, Liron Reshef-Steinberger, Idan Zin, Alon Shaul, Meital Zilberman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Natural derived biopolymers such as soy protein are promising candidates for a variety of biomedical applications and attract an increasing interest of the biomedical society worldwide. In the current study, novel soy protein films loaded with the analgesic drug bupivacaine were developed and studied for the effect of the formulation parameters on their properties. They exhibited tailorable mechanical and physical properties, biocompatibility and desired drug release profile. Hence, they can potentially be useful for wound coverage applications and also for treating various conditions where local pain is involved, such as in inflammation resulting from a disease or injury.

Original languageEnglish
Pages (from-to)345-355
Number of pages11
JournalInternational Journal of Polymeric Materials and Polymeric Biomaterials
Volume70
Issue number5
DOIs
StatePublished - 2021

Funding

FundersFunder number
Medical Corps of the Israeli Defense Forces
International Dragonfly Fund

    Keywords

    • Drug delivery
    • soy protein
    • wound dressing

    Fingerprint

    Dive into the research topics of 'Mechanical, physical and biological characterization of soy protein films loaded with bupivacaine for wound healing applications'. Together they form a unique fingerprint.

    Cite this