Measurement of the fetal umbilical cord insertion-to-genital tubercle length in early gestation :In utero sonographic study

Yinon Gilboa, Eldad Katorza, Alon Kedem, Maya Spira, Reuven Achiron

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives-The purpose of this study was to establish in utero reference ranges for the fetal umbilical cord insertion-to-genital tubercle length in early gestation. Methods-A prospective cross-sectional study was performed on 140 normal low-risk singleton pregnancies between 12 and 18 weeks' gestation. The umbilical cord insertion- to-genital tubercle length was measured in a midsagittal section with high-resolution transvaginal or transabdominal sonography. The mean and 95% prediction limits were defined for each gestational week and analyzed by regression equations and correlation coefficients. Results-Adequate measurements were obtained in 134 patients. The umbilical cord insertion-to-genital tubercle length as a function of gestational age was expressed by the following regression equation: umbilical cord insertion-to-genital tubercle length = -3.079452 + 1.09 × week (R 2 = 0.7117). The correlation R2 = 0.7117 was found to be highly statistically significant (P< .001). The normal mean and 95% prediction limits were defined for each gestational week. During the study period, 2 cases were referred to our unit because of nonvisualization of the urinary bladder. The umbilical cord insertion- to-genital tubercle lengths in these cases were below the 95th percentile, confirming the diagnosis of bladder exstrophy. Conclusions-The normative data established in this study may be helpful for early prenatal diagnosis congenital bladder exstrophy.

Original languageEnglish
Pages (from-to)237-241
Number of pages5
JournalJournal of Ultrasound in Medicine
Volume30
Issue number2
DOIs
StatePublished - 1 Feb 2011

Keywords

  • Bladder exstrophy
  • Fetus
  • Sonography

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