Measurement of intrauterine human decidua-associated protein 200 and diagnosis of ectopic pregnancy

Reuvit Halperin*, Eran Hadas, Ian Bukovsky, David Schneider

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of the current study was to examine whether the measurement of intrauterine human decidua-associated protein (hDP) 200 might be of clinical value in the diagnosis of ectopic pregnancy versus early missed abortion. Uterine fluid levels of hDP 200 were measured in two groups of patients: 20 women with ectopic pregnancy, diagnosed by laparoscopy, and 20 women diagnosed (after curettage) as having a missed abortion. No significant difference in hDP 200 levels was observed comparing patients with ectopic pregnancy (mean 114.0 ± 58.2 mU/ml) and patients with early missed abortion (mean 222.0 ± 116.0 mU/ml), although a trend towards lower levels of uterine fluid hDP 200 was noted in the group of patients presenting with tubal pregnancy. Thus, according to our data, intrauterine hDP 200 is not sufficiently discriminative to be of clinical value in the diagnosis of ectopic pregnancy.

Original languageEnglish
Pages (from-to)225-228
Number of pages4
JournalGynecologic and Obstetric Investigation
Volume45
Issue number4
DOIs
StatePublished - 1998
Externally publishedYes

Keywords

  • Ectopic pregnancy
  • Human decidua-associated protein 200
  • Missed abortion
  • Uterine fluid

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