TY - JOUR
T1 - Maternal thrombophilia and adverse pregnancy outcomes
AU - Weintraub, Adi Y.
AU - Press, Fernanda
AU - Wiznitzer, Arnon
AU - Sheiner, Eyal
PY - 2007/3/1
Y1 - 2007/3/1
N2 - Thrombophilias are inherited or acquired conditions that predispose an individual to thromboembolism. During pregnancy, maternal thrombophilia has been identified as a major risk factor for adverse pregnancy outcomes (APO), including venous and arterial thrombosis, preeclampsia, placental abruption, intrauterine growth restriction, intrauterine fetal losses and recurrent miscarriages. Although a great body of evidence has accumulated regarding this association, there is still much controversy. In this review, aspects of certain APO and thrombophilia are discussed, as well as prophylactic and therapeutic implications.
AB - Thrombophilias are inherited or acquired conditions that predispose an individual to thromboembolism. During pregnancy, maternal thrombophilia has been identified as a major risk factor for adverse pregnancy outcomes (APO), including venous and arterial thrombosis, preeclampsia, placental abruption, intrauterine growth restriction, intrauterine fetal losses and recurrent miscarriages. Although a great body of evidence has accumulated regarding this association, there is still much controversy. In this review, aspects of certain APO and thrombophilia are discussed, as well as prophylactic and therapeutic implications.
KW - adverse pregnancy outcomes
KW - antiphospholipid syndrome
KW - low-molecular-weight heparin
KW - thrombophilia
UR - http://www.scopus.com/inward/record.url?scp=35649026929&partnerID=8YFLogxK
U2 - 10.1586/17474108.2.2.203
DO - 10.1586/17474108.2.2.203
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AN - SCOPUS:35649026929
SN - 1747-4108
VL - 2
SP - 203
EP - 216
JO - Expert Review of Obstetrics and Gynecology
JF - Expert Review of Obstetrics and Gynecology
IS - 2
ER -
