Abstract
Electroporation is a biophysical phenomenon in which cell membrane permeability is increased through externally applied pulsed electric fields. This membrane permeability increase is used for many applications in biotechnology, medicine and the food industry. Understanding the transport phenomena through the cell membrane during electroporation is critical for the successful implementation of the electroporation. This chapter focuses primarily on mathematical models of mass transfer related to cell electroporation. The goal of the chapter is also to provide the reader with an introduction to electroporation-mediated mass transport to cells and tissues, and to facilitate a fundamental understanding of the models.
Original language | English |
---|---|
Title of host publication | Transport in Biological Media |
Publisher | Elsevier Inc. |
Pages | 455-492 |
Number of pages | 38 |
ISBN (Print) | 9780124158245 |
DOIs | |
State | Published - May 2013 |
Externally published | Yes |
Keywords
- Electrodiffusion
- Electropermeabilization
- Electroporation
- Mass transport
- Mathematical models
- Pulsed electric fields