Mass Transfer Phenomena in Electroporation

Alexander Golberg, Boris Rubinsky

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Electroporation is a biophysical phenomenon in which cell membrane permeability is increased through externally applied pulsed electric fields. This membrane permeability increase is used for many applications in biotechnology, medicine and the food industry. Understanding the transport phenomena through the cell membrane during electroporation is critical for the successful implementation of the electroporation. This chapter focuses primarily on mathematical models of mass transfer related to cell electroporation. The goal of the chapter is also to provide the reader with an introduction to electroporation-mediated mass transport to cells and tissues, and to facilitate a fundamental understanding of the models.

Original languageEnglish
Title of host publicationTransport in Biological Media
PublisherElsevier Inc.
Pages455-492
Number of pages38
ISBN (Print)9780124158245
DOIs
StatePublished - May 2013
Externally publishedYes

Keywords

  • Electrodiffusion
  • Electropermeabilization
  • Electroporation
  • Mass transport
  • Mathematical models
  • Pulsed electric fields

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