Mapping of unconventional myosins in mouse and human

Tama Hasson, Joseph F. Skowron, Debra J. Gilbert, Karen B. Avraham, William L. Perry, William M. Bement, Blake L. Anderson, Elliott H. Sherr, Zheng Yi Chen, Lloyd A. Greene, David C. Ward, David P. Corey, Mark S. Mooseker, Neal G. Copeland, Nancy A. Jenkins*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Myosins are molecular motors that move along filamentous actin. Seven classes of myosin are expressed in vertebrates: conventional myosin, or myosin-II, as well as the 6 unconventional myosin classes -I, -V, -VI, VII, - IX, and -X. We have mapped in mouse 22 probes encompassing all known unconventional myosins and, as a result, have identified 16 potential unconventional myosin genes. These genes include 7 myosins-I, 2 myosins-V, 1 myosin-VI, 3 myosins-VII, 2 myosins-IX, and 1 myosin-X. The map location of 5 of these genes was identified in human chromosomes by fluorescence in situ hybridization.

Original languageEnglish
Pages (from-to)431-439
Number of pages9
Issue number3
StatePublished - 15 Sep 1996
Externally publishedYes


FundersFunder number
Deaf- ness Research Foundation
National Institutes of HealthDK38979, DK25387
Howard Hughes Medical Institute
U.S. Department of Health and Human Services
National Cancer Institute
National Institute of Neurological Disorders and StrokeR01NS033689
Muscular Dystrophy Association


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