Mapping a Neutralizing Epitope on the SARS Coronavirus Spike Protein: Computational Prediction Based on Affinity-selected Peptides

Keyphrases

• Coronavirus Spike Protein 100%
• Spike Protein 100%
• Prediction Method 100%
• Neutralizing Epitope 100%
• Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) 100%
• Computational Prediction 100%
• Random Peptide Library 66%
• Neutralizing Antigen Epitope 66%
• Emerging Viral Pathogen 33%
• Virus 33%
• Amino Acid Pairs 33%
• Deconvoluted 33%
• Discontinuous Epitope 33%
• Cysteine 33%
• Severe Acute Respiratory Syndrome 33%
• Rational Design of Vaccines 33%
• Computer Algorithm 33%
• Monoclonal Antibody 33%
• Highly Pathogenic Avian Influenza H5N1 33%
• Combined Test 33%
• Entry Inhibitor 33%
• Peptide Pools 33%

Immunology and Microbiology

• Spike 100%
• Epitope 100%
• SARS Coronavirus 100%
• Crystal Structure 40%
• Neutralizing Antibody 40%
• Peptide Library 40%
• Monoclonal Antibody 20%
• Bird 20%
• Influenza A Virus (H5N1) 20%
• Severe Acute Respiratory Syndrome 20%
• Vaccine Efficacy 20%
• SARS-related Coronavirus 20%
• Infectious Agent 20%
• Phage Display 20%