Management of labor in patients with idiopathic thrombocytopenic purpura

U. Dan, G. Barkai, B. David, M. Goldenberg, E. Kukkia, S. Mashiach

Research output: Contribution to journalArticlepeer-review


Transient thrombocytopenia may occur in infants born to mothers with idiopathic thrombocytopenic purpura, suggesting transplacental passage of the antiplatelet factor. Labor in women with idiopathic thrombocytopenic purpura calls for a special management. Irrespective of the maternal platelet count, we believe that labor should be conducted vaginally but reassessed after a thrombocyte count of fetal scalp blood. Maternal thrombocytopenia, which may indicate a possible risk of coagulopathy, should be treated aggressively and followed up with replacement therapy. Percutaneous umbilical sampling is to be avoided because it carries an immediate risk of fetal and maternal complications. A count of 50,000/mm3, obtained early during the course of labor, may be taken as a threshold indicator for abdominal delivery via cesarean section.

Original languageEnglish
Pages (from-to)193-196
Number of pages4
JournalGynecologic and Obstetric Investigation
Issue number4
StatePublished - 1989
Externally publishedYes


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