Malignant Melanoma in Association with a Thymic Nevus in a Patient with a Giant Congenital Nevus

Yulia Shvartser-Beryozkin; Alexander Yakobson; Daniel Benharroch; Milton Saute; Meora Feinmesser

doi:10.1097/DAD.0000000000000817

Malignant Melanoma in Association with a Thymic Nevus in a Patient with a Giant Congenital Nevus

Yulia Shvartser-Beryozkin^*, Alexander Yakobson, Daniel Benharroch, Milton Saute, Meora Feinmesser

^*Corresponding author for this work

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Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Nevi and melanocytic proliferations are known to appear in multiple extracutaneous sites, including lymph nodes and meninges. We report a case of an anterior mediastinal mass in a patient with a giant congenital nevus and neurofibromatosis type I. Histologically, the tumor was found to be a malignant melanoma in the thymus arising in association with a nevus that involved most of the thymic tissue. There was no sign of cutaneous melanoma on skin examination. We suggest that the tumor originated from the benign nevus in the thymus, a rare extracutaneous location for nevi and malignant melanoma.

Original language	English
Pages (from-to)	538-541
Number of pages	4
Journal	American Journal of Dermatopathology
Volume	39
Issue number	7
DOIs	https://doi.org/10.1097/DAD.0000000000000817
State	Published - 1 Jul 2017

Keywords

extracutaneous nevus
giant pigmented nevus
malignant melanoma
thymus

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10.1097/DAD.0000000000000817

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abstract = "Nevi and melanocytic proliferations are known to appear in multiple extracutaneous sites, including lymph nodes and meninges. We report a case of an anterior mediastinal mass in a patient with a giant congenital nevus and neurofibromatosis type I. Histologically, the tumor was found to be a malignant melanoma in the thymus arising in association with a nevus that involved most of the thymic tissue. There was no sign of cutaneous melanoma on skin examination. We suggest that the tumor originated from the benign nevus in the thymus, a rare extracutaneous location for nevi and malignant melanoma.",

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AU - Shvartser-Beryozkin, Yulia

AU - Yakobson, Alexander

AU - Benharroch, Daniel

AU - Saute, Milton

AU - Feinmesser, Meora

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N2 - Nevi and melanocytic proliferations are known to appear in multiple extracutaneous sites, including lymph nodes and meninges. We report a case of an anterior mediastinal mass in a patient with a giant congenital nevus and neurofibromatosis type I. Histologically, the tumor was found to be a malignant melanoma in the thymus arising in association with a nevus that involved most of the thymic tissue. There was no sign of cutaneous melanoma on skin examination. We suggest that the tumor originated from the benign nevus in the thymus, a rare extracutaneous location for nevi and malignant melanoma.

AB - Nevi and melanocytic proliferations are known to appear in multiple extracutaneous sites, including lymph nodes and meninges. We report a case of an anterior mediastinal mass in a patient with a giant congenital nevus and neurofibromatosis type I. Histologically, the tumor was found to be a malignant melanoma in the thymus arising in association with a nevus that involved most of the thymic tissue. There was no sign of cutaneous melanoma on skin examination. We suggest that the tumor originated from the benign nevus in the thymus, a rare extracutaneous location for nevi and malignant melanoma.

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KW - giant pigmented nevus

KW - malignant melanoma

KW - thymus

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Malignant Melanoma in Association with a Thymic Nevus in a Patient with a Giant Congenital Nevus

Abstract

Keywords

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