Malignant Melanoma in Association with a Thymic Nevus in a Patient with a Giant Congenital Nevus

Yulia Shvartser-Beryozkin*, Alexander Yakobson, Daniel Benharroch, Milton Saute, Meora Feinmesser

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Nevi and melanocytic proliferations are known to appear in multiple extracutaneous sites, including lymph nodes and meninges. We report a case of an anterior mediastinal mass in a patient with a giant congenital nevus and neurofibromatosis type I. Histologically, the tumor was found to be a malignant melanoma in the thymus arising in association with a nevus that involved most of the thymic tissue. There was no sign of cutaneous melanoma on skin examination. We suggest that the tumor originated from the benign nevus in the thymus, a rare extracutaneous location for nevi and malignant melanoma.

Original languageEnglish
Pages (from-to)538-541
Number of pages4
JournalAmerican Journal of Dermatopathology
Volume39
Issue number7
DOIs
StatePublished - 1 Jul 2017

Keywords

  • extracutaneous nevus
  • giant pigmented nevus
  • malignant melanoma
  • thymus

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