Malign effects of splenectomy-the place of conservative treatment

Nahum Werbin*, Kiran Lodha

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


In this review article the incidence is discussed of overwhelming post-splenectomy infection (OPSI), which is especially likely to occur in children and when splenectomy is carried out for haematological disorders. Long-term broad spectrum antibiotics or the use of polyvalent pneumococcal vaccine are often advocated as prophylactic measures under these circumstances. After mild splenic trauma, conservative surgery or partial splenectomy may be indicated in some cases. Where trauma is more severe and the spleen cannot safely be preserved there may be a place for autotransplantation of splenic slices, for example into a pocket of omentum, and there is some experimental support for this technique.

Original languageEnglish
Pages (from-to)65-69
Number of pages5
JournalPostgraduate Medical Journal
Issue number676
StatePublished - 1982
Externally publishedYes


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