Lysozyme levels in human tears

Rahamim Avisar*, Hanna Savir, Pnina Shaked, Raoul Menache, Haim Levinsky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Tears collected from 69 healthy subjects (138 eyes) with normal fluid tear secretion were analyzed by our lysozyme plate method. The enzyme titer was estimated as well. Lysozyme levels in basal tear fluid ranged from 2400 to 10,000 μg/mL of hen-egg-white lysozyme activity (HEL). In stimulated tear fluid, induced by ammonia inhalation, the enzyme level fell dramatically and appeared to reach a minimum around 1195 μg/mL HEL. Lysozyme concentration in tears of healthy human subjects depends on the flow rate of tear secretion. Even when the lysozyme level was low in stimulated tears, it has a potential anti-inflammatory role.

Original languageEnglish
Pages (from-to)231-232
Number of pages2
JournalAnnals of Ophthalmology - Glaucoma
Issue number4-5
StatePublished - Jul 1999
Externally publishedYes


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