Lysosome targeting fluorescence probe for imaging intracellular thiols

Dnyaneshwar Kand, Tanmoy Saha, Mayurika Lahiri, Pinaki Talukdar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A BODIPY-based fluorescence turn-on probe, exhibiting high selectivity and sensitivity towards intracellular thiols with excellent lysosomal localization is reported. The probe displayed fast response towards biothiols in aqueous solution. Localization of the probe in lysosome was demonstrated by intracellular colocalization studies with the aid of LysoSensor Green.

Original languageEnglish
Pages (from-to)8163-8168
Number of pages6
JournalOrganic and Biomolecular Chemistry
Volume13
Issue number30
DOIs
StatePublished - 14 Aug 2015
Externally publishedYes

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