Lymphoid Leukemias

Moshe E. Gatt; Shai Izraeli

doi:10.1016/B978-0-7020-6896-6.00078-8

Lymphoid Leukemias

Moshe E. Gatt, Shai Izraeli

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are the two most common leukemias of the immune system. Each of these diseases is characterized by diverse somatic driving aberrations of significant prognostic significance, and these are used for risk stratification and adjustment of therapy. Recent advances in the science of immunology have resulted in dramatic development of new and effective therapies for patients with these malignancies.

Original language	English
Title of host publication	Clinical Immunology
Subtitle of host publication	Principles and Practice
Publisher	Elsevier
Pages	1049-1063.e1
ISBN (Electronic)	9780702068966
ISBN (Print)	9780702070396
DOIs	https://doi.org/10.1016/B978-0-7020-6896-6.00078-8
State	Published - 1 Jan 2019
Externally published	Yes

Keywords

Acute lymphoblastic leukemia
B-cell receptor signaling
Chronic lymphocytic leukemia
Clonal diversity
Immunotherapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-7020-6896-6.00078-8

Cite this

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AB - Acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) are the two most common leukemias of the immune system. Each of these diseases is characterized by diverse somatic driving aberrations of significant prognostic significance, and these are used for risk stratification and adjustment of therapy. Recent advances in the science of immunology have resulted in dramatic development of new and effective therapies for patients with these malignancies.

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KW - B-cell receptor signaling

KW - Chronic lymphocytic leukemia

KW - Clonal diversity

KW - Immunotherapy

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Lymphoid Leukemias

Abstract

Keywords

UN SDGs

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