TY - JOUR
T1 - Lymphocytes Bearing Surface Ferritin in Patients with Hodgkin's Disease and Breast Cancer
AU - Moroz, Chaya
AU - Giler, Shamai
AU - Kupfer, Batia
AU - Urca, Israel
AU - Ramot, B.
AU - Biniamiov, M.
AU - Rosenthal, E.
AU - Ben-Bassat, I.
AU - Aghai, E.
PY - 1977/5/19
Y1 - 1977/5/19
N2 - To the Editor: In a recent editorial (N Engl J Med 295:1314–1315, 1976) Dr. Siegal reviewed the possible inhibitors of T-cell rosette formation prevalent in serum of patients with Hodgkin's disease. Among others, he mentioned our findings, in which, by enzymic radioiodination of Hodgkin-disease lymphocytes, we demonstrated ferritin on the surface of the cells. The iodinated ferritin was shed into the culture medium after incubation with levamisole, resulting in unmasking of normal surface proteins.1 The possibility was raised that a subpopulation of T cells exists that is specifically sensitive to inhibition of rosette formation by the inhibitor. Indeed, in.
AB - To the Editor: In a recent editorial (N Engl J Med 295:1314–1315, 1976) Dr. Siegal reviewed the possible inhibitors of T-cell rosette formation prevalent in serum of patients with Hodgkin's disease. Among others, he mentioned our findings, in which, by enzymic radioiodination of Hodgkin-disease lymphocytes, we demonstrated ferritin on the surface of the cells. The iodinated ferritin was shed into the culture medium after incubation with levamisole, resulting in unmasking of normal surface proteins.1 The possibility was raised that a subpopulation of T cells exists that is specifically sensitive to inhibition of rosette formation by the inhibitor. Indeed, in.
UR - http://www.scopus.com/inward/record.url?scp=0017778995&partnerID=8YFLogxK
U2 - 10.1056/NEJM197705192962017
DO - 10.1056/NEJM197705192962017
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AN - SCOPUS:0017778995
SN - 0028-4793
VL - 296
SP - 1172
EP - 1174
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 20
ER -
