Lyme neuroborreliosis: infection, immunity, and inflammation

Andrew R. Pachner, Israel Steiner

Research output: Contribution to journalReview articlepeer-review

Abstract

Lyme neuroborreliosis (LNB), the neurological manifestation of systemic infection with the complex spirochaete Borrelia burgdorferi, can pose a challenge for practising neurologists. This Review is a summary of clinical presentation, diagnosis, and therapy, as well as of recent advances in our understanding of LNB. Many new insights have been gained through work in experimental models of the disease. An appreciation of the genetic heterogeneity of the causative pathogen has helped clinicians in their understanding of the diverse presentations of LNB.

Original languageEnglish
Pages (from-to)544-552
Number of pages9
JournalThe Lancet Neurology
Volume6
Issue number6
DOIs
StatePublished - Jun 2007
Externally publishedYes

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