Lower brain-derived neurotrophic factor in serum of relapsing remitting MS: Reversal by glatiramer acetate

David Azoulay, Veronika Vachapova, Boris Shihman, Ariel Miler, Arnon Karni*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Neuronal growth factors may exert a neuroprotective effect in multiple sclerosis (MS). We found reduced levels of brain-derived neurotrophic factors (BDNF) in the serum and CSF of relapsing-remitting MS patients, which was reversed by therapy with glatiramer acetate. BDNF may play a protective role in MS, and immunomodulation therapy, such as with glatiramer acetate, may enhance the action this mechanism.

Original languageEnglish
Pages (from-to)215-218
Number of pages4
JournalJournal of Neuroimmunology
Volume167
Issue number1-2
DOIs
StatePublished - Oct 2005

Keywords

  • Brain-derived neurotrophic factor
  • Glatiramer acetate
  • Multiple sclerosis
  • Neuroprotection

Fingerprint

Dive into the research topics of 'Lower brain-derived neurotrophic factor in serum of relapsing remitting MS: Reversal by glatiramer acetate'. Together they form a unique fingerprint.

Cite this