TY - JOUR
T1 - Low serum C3, leukopenia, and thrombocytopenia
T2 - Unusual features of Henoch-Schonlein purpura
AU - Krause, I.
AU - Garty, B. Z.
AU - Davidovits, M.
AU - Cleper, R.
AU - Tamary, H.
AU - Rosenmann, E.
AU - Eisenstein, B.
PY - 1999
Y1 - 1999
N2 - Henoch-Schonlein purpura (HSP) affects predominantly the skin, joints, gastrointestinal tract and kidney. Although the pathogenesis is probably of immune origin and complement activation is thought to play a role, laboratory findings including the serum level of the complement components are usually normal. We present a patient with a severe form of HSP nephritis who had unusual laboratory findings of a low level of C3, mild leukopenia and thrombocytopenia. These findings may further support the importance of complement activation in the pathogenesis of HSP.
AB - Henoch-Schonlein purpura (HSP) affects predominantly the skin, joints, gastrointestinal tract and kidney. Although the pathogenesis is probably of immune origin and complement activation is thought to play a role, laboratory findings including the serum level of the complement components are usually normal. We present a patient with a severe form of HSP nephritis who had unusual laboratory findings of a low level of C3, mild leukopenia and thrombocytopenia. These findings may further support the importance of complement activation in the pathogenesis of HSP.
KW - C3
KW - Henoch-Schonlein purpura
KW - Hypocomplementemia
KW - Nephritis
UR - http://www.scopus.com/inward/record.url?scp=0032822644&partnerID=8YFLogxK
U2 - 10.1007/s004310051239
DO - 10.1007/s004310051239
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AN - SCOPUS:0032822644
SN - 0340-6199
VL - 158
SP - 906
EP - 909
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
IS - 11
ER -