TY - JOUR
T1 - Low Plasma Immunoreactive β‐Endorphin Levels in Autism
AU - WEIZMAN, RONIT
AU - GIL-AD, IRIT
AU - DICK, JACOB
AU - TYANO, SAM
AU - SZEKELY, GEORGE A.
AU - LARON, ZVI
PY - 1988
Y1 - 1988
N2 - Baseline morning basal plasma immunoreactive β-endorphin (ir-β-EP) level was assayed in 22 autistic, 22 schizophrenic, and 22 control subjects. Eight autistics and eight schizophrenics were drug-free while the remaining patients were maintained on neuroleptic treatment. The mean values of ir-β-EP were significantly lower in unmedicated and medicated autistics compared to age- and sex-matched schizophrenics and healthy controls. Unaltered ir-β-EP levels were observed in untreated schizophrenics, while neuroleptic treatment induced a significant elevation of the opioid levels. A lower ir-β-EP elevation was achieved by neuroleptics in autistics when compared to treated schizophrenics. J. Am. Acad. Child Adolesc. Psychiatry, 1988, 27, 4:430–433.
AB - Baseline morning basal plasma immunoreactive β-endorphin (ir-β-EP) level was assayed in 22 autistic, 22 schizophrenic, and 22 control subjects. Eight autistics and eight schizophrenics were drug-free while the remaining patients were maintained on neuroleptic treatment. The mean values of ir-β-EP were significantly lower in unmedicated and medicated autistics compared to age- and sex-matched schizophrenics and healthy controls. Unaltered ir-β-EP levels were observed in untreated schizophrenics, while neuroleptic treatment induced a significant elevation of the opioid levels. A lower ir-β-EP elevation was achieved by neuroleptics in autistics when compared to treated schizophrenics. J. Am. Acad. Child Adolesc. Psychiatry, 1988, 27, 4:430–433.
KW - autism
KW - immunoreactive-β-endorphin
KW - neuroleptics
KW - schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=0023807212&partnerID=8YFLogxK
U2 - 10.1097/00004583-198807000-00009
DO - 10.1097/00004583-198807000-00009
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C2 - 2972691
AN - SCOPUS:0023807212
SN - 0890-8567
VL - 27
SP - 430
EP - 433
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
IS - 4
ER -