@article{1618063d34d9436cac6effb969ec6aa0,
title = "Long-term verapamil treatment increases [3H]imipramine binding in human platelets",
abstract = "The effect of long-term verapamil treatment on [3H]imipramine binding to the serotonin transporter in human platelets was studied. A significant increase (24%, P<0.05) in the density of high-affinity imipramine binding sites was observed in platelets of cardiac patients maintained exclusively on verapamil. The up-regulation of the serotonin transporter may be relevant to the previously reported beneficial effect of verapamil in affective disorders.",
keywords = "5-HT transporter, Imipramine binding, Platelets, Verapamil",
author = "Adi Cohen and Abraham Weizman and Michael Eldar and Moshe Rehavi",
note = "Funding Information: This research was supported by the Basic Research Foundation administered by the Israeli Academy of Sciences and Humanities and by the Chief Scientist of the Israeli Ministry of Health.",
year = "1990",
month = jun,
day = "8",
doi = "10.1016/0014-2999(90)90096-O",
language = "אנגלית",
volume = "181",
pages = "311--314",
journal = "European Journal of Pharmacology",
issn = "0014-2999",
publisher = "Elsevier B.V.",
number = "3",
}