Long-term outcomes in patients initially responsive to selective laser trabeculoplasty

Varun Patel, Eman El Hawy, Michael Waisbourd, Camila Zangalli, Daniel M. Shapiro, Lalita Gupta, Michael Hsieh, Abigail Kasprenski, L. Jay Katz, George L. Spaeth*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

•AIM: To determine the long-term effects of selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) and the number of medications used up to 5y following treatment in glaucoma patients receiving maximally tolerated medical therapy (MTMT). •METHODS: The Wills Eye Hospital Glaucoma Research Center retrospectively reviewed the charts of glaucoma patients who underwent SLT after receiving MTMT. Eyes that did not achieve their target pressure within 3mo following SLT were excluded from the study. Changes in mean IOP and number of glaucoma medications used were analyzed at 1, 3, and 5y following SLT. •RESULTS: Seventy-five eyes of 67 patients were included in the study. Fifteen eyes that received SLT failed to achieve their target pressure within 3mo and were excluded from the study. The average follow-up time was 37.4mo (±14.4). Mean IOP was significantly reduced 1y after treatment (P=0.005). It was also reduced 3, 5y after treatment without reaching statistical significance (P=0.20 and P=0.072, respectively). There was a significant decrease in mean number of medications used 1, 3, 5y after treatment (P<0.001, P<0.001, and P=0.039, respectively). In the span of 5y, 2 eyes (2.7%) underwent repeat SLT, 7 eyes (9.3%) underwent glaucoma surgery and an additional 3 eyes (4.0%) underwent both. •CONCLUSION: SLT significantly reduced the number of glaucoma medications used 5y following treatment in glaucoma patients receiving MTMT. SLT may delay operating-room surgery.

Original languageEnglish
Pages (from-to)960-964
Number of pages5
JournalInternational Journal of Ophthalmology
Volume8
Issue number5
DOIs
StatePublished - 18 Oct 2015
Externally publishedYes

Keywords

  • Glaucoma
  • Intraocular pressure
  • Long-term
  • Maximally tolerated medical therapy
  • Number of medications used
  • Selective laser trabeculoplasty

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