@article{a7d1de662ce1478e8adef52b81c7f53e,
title = "Long-term interactions between endogenous and exogenous opiates",
abstract = "The in vitro biological effect of various opiates was studied in the guinea pig ileum bioassay. Besides their direct, immediate effect, certain opiates induced sensitivity changes whichpersisted after their removal and the complete recovery of the preparation. These specific, asymmetrical interactions may represent long-term modulation of the opiate receptor. The in vivo pharmacological implication of opiate interaction is discussed.",
keywords = "Drug interaction, Endorphin, Enkephalin, Morphine, opiates",
author = "Yosef Sarne and Yehoshua Gothilf and Weissman, {Ben Avi}",
note = "Funding Information: This study was supported by the Israel Center for Psychobiology, The Charles Smith Foundation Grant 17/79 to Y.S.",
year = "1980",
month = mar,
day = "7",
doi = "10.1016/0014-2999(80)90488-4",
language = "אנגלית",
volume = "62",
pages = "117--120",
journal = "European Journal of Pharmacology",
issn = "0014-2999",
publisher = "Elsevier B.V.",
number = "1",
}