Long-term health-related quality of life after mandibular resection and reconstruction

Anton Warshavsky*, Dan M. Fliss, Gal Frenkel, Aviv Kupershmidt, Nuphar Moav, Roni Rosen, Melissa Sechter, Udi Shapira, Sara Abu-Ghanem, Moshe Yehuda, Arik Zaretski, Ravit Yanko-Arzi, Vadim Reiser, Gilad Horowitz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Purpose: To compare short- and long-term quality of life (QOL) scores in patients undergoing mandibular resection and reconstruction. Materials and methods: All the patients who underwent resection and reconstruction of the mandible between 2000 and 2015 at a large tertiary center were retrospectively reviewed. Their QOL was measured by the University of Washington QOL questionnaire. Between 12 and 189 months (median 83.5 months) had elapsed since the end of treatment. The QOL of the short-term (< 5 years) and long-term (> 5 years) follow-up groups was compared and analyzed. Results: Fifty-eight patients completed the questionnaire. The scores for physical function, emotional function, activity, recreation, and taste domains were significantly higher for the long-term follow-up group. The activity and pain domains posed a significant problem for significantly more patients in the short-term follow-up group. Conclusion: Comparison of the short- and long-term QOL scores of patients undergoing mandibular resection and reconstruction revealed that the scores for the latter were significantly higher in several domains. This finding might be indicative of a cumulative effect of time on patients’ QOL, even many years post-treatment.

Original languageEnglish
Pages (from-to)1501-1508
JournalEuropean Archives of Oto-Rhino-Laryngology
StatePublished - 1 May 2019


  • Follow-up
  • Long term
  • Mandibulectomy
  • Quality of life (QOL)


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