Long-term assessment of pulmonary function tests in pediatric survivors of acute respiratory distress syndrome

Ron Ben Abraham, Avi A. Weinbroum, Hector Roizin, Ori Efrati, Arie Augarten, Ran Harel, Osnat Moreh, Zohar Barzilay, Gideon Paret

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The aim of the study was to evaluate long-term pulmonary function tests in pediatric survivors of acute respiratory distress syndrome (ARDS). Material/Methods: Observational study based on a telephone poll of retrospectively identified post ARDS children who were hospitalized in a pediatric intensive care unit (PICU) in a general 1200-bed teaching, tertiary, regional referral center for children. Results: Follow-up pulmonary function tests were achieved in only 7 children, with a mean age of 7.3±4.3 years (range 3-12) and following 5.6±4.3 years after PICU discharge. The etiology for ARDS included: lymphoma (n=2), pneumonia (n=2), aspiration (n=1), petrol ingestion (n=1) and snake envenomation (n=1). The children had been ventilated for 9.4±7.3 days and their worst PaO2/FiO2 ratio was 65.1±17.0 mm Hg. The follow-up pulmonary functions in all the children was within normal limits except for one child who had mildly reduced DLCO and one who had mild exercise-induced hypoxemia (oxyhemoglobin saturation of 94%). Neither of the two nor the others showed subjective symptoms or clinical physical limitations. Conclusions: Children who survive ARDS apparently enjoy long-term normal pulmonary function. Some, however, may present subclinical dysfunction that persists for many years after the acute episode and evoked only by sophisticated lung tests.

Original languageEnglish
Pages (from-to)CR153-CR157
JournalMedical Science Monitor
Volume8
Issue number3
StatePublished - 2002
Externally publishedYes

Keywords

  • ARDS
  • Pediatric
  • Prognosis
  • Pulmonary function tests

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