TY - JOUR
T1 - Local methotrexate injection
T2 - A nonsurgical treatment of ectopic pregnancy
AU - Pansky, Mordechai
AU - Bukovsky, Ian
AU - Golan, Abraham
AU - Langer, Rami
AU - Schneider, David
AU - Arieli, Shlomo
AU - Caspi, Eliahu
PY - 1989/8
Y1 - 1989/8
N2 - Twenty seven patients with unruptured tubal pregnancy were selected for nonsurgical treatment with the use of one injection of 12.5 mg of methotrexate into the ectopic site at laparoscopy. No adverse reactions were observed. In three patients (11%), a laparotomy was performed because of rising β-human chorionic gonadotropin titers. In the other patients, serum β-human chorionic gonadotropin levels decreased to the nonpregnant range with no further intervention, and the patients recovered uneventfully. This method is suggested as an alternative to surgery in selected cases of early unruptured tubal pregnancy.
AB - Twenty seven patients with unruptured tubal pregnancy were selected for nonsurgical treatment with the use of one injection of 12.5 mg of methotrexate into the ectopic site at laparoscopy. No adverse reactions were observed. In three patients (11%), a laparotomy was performed because of rising β-human chorionic gonadotropin titers. In the other patients, serum β-human chorionic gonadotropin levels decreased to the nonpregnant range with no further intervention, and the patients recovered uneventfully. This method is suggested as an alternative to surgery in selected cases of early unruptured tubal pregnancy.
KW - Local methotrexate
KW - tubal pregnancy
UR - http://www.scopus.com/inward/record.url?scp=0024397175&partnerID=8YFLogxK
U2 - 10.1016/0002-9378(89)90529-2
DO - 10.1016/0002-9378(89)90529-2
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AN - SCOPUS:0024397175
SN - 0002-9378
VL - 161
SP - 393
EP - 396
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
IS - 2
ER -