Local electrographic effects of Leu-enkephalin microinjections into the brain

Z. Elazar, R. Simantov, E. Motles

Research output: Contribution to journalArticlepeer-review

Abstract

Microinjections of Leu-enkephalin were made in dorsal hippocampus, caudate nucleus, amygdala, nucleus accumbens and parietal cortex in rats. The effects of enkephalin on the local electrical activity recorded from the area of the microinjection are described. Depression effects (attenuation of amplitudes and slowing) were recorded in caudate nucleus, nucleus accumbens, amygdala and parietal cortex, but not in hippocampus. Activation and epileptiform effects (spikes, seizures) were recorded from all structures studied.

Original languageEnglish
Pages (from-to)91-95
Number of pages5
JournalElectroencephalography and Clinical Neurophysiology
Volume54
Issue number1
DOIs
StatePublished - Jul 1982

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