Liver support systems

Patrick Sorkine, Ron Ben Abraham, Shlomo Brill, Oded Szold*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


In recent years liver transplantation was shown to be the only clinically effective method of treating acute or chronic hepatic failure due to various causes. However, this ultimate therapeutic approach is limited by the growing disparity between organ donation and the number of patients on the waiting list. Factors such as high cost, morbidity, and the need for lifelong immunosuppression accelerated the research on alternative methods to support the failing liver. Recently, new technologies incorporating hepatocytes and extracorporeal circulation devices were introduced for liver support. This review presents current knowledge on liver support systems and their role in the treatment of acute liver failure.

Original languageEnglish
Pages (from-to)44-49
Number of pages6
JournalIsrael Medical Association Journal
Issue number1
StatePublished - 2001
Externally publishedYes


  • Acute liver failure
  • Bioartificial liver support systems
  • Extracorporeal blood purification


Dive into the research topics of 'Liver support systems'. Together they form a unique fingerprint.

Cite this