Listeriosis in human pregnancy: A systematic review

Ronald F. Lamont, Jack Sobel, Shali Mazaki-Tovi, Juan Pedro Kusanovic, Edi Vaisbuch, Sun Kwon Kim, Niels Uldbjerg, Roberto Romero

Research output: Contribution to journalReview articlepeer-review

Abstract

Listeria is commonly found in processed and prepared foods and listeriosis is associated with high morbidity and mortality. Preventative measures are well prescribed and monitoring and voluntary recall of contaminated products has resulted in a 44% reduction in the prevalence of perinatal listeriosis in the USA. Pregnant women are at high risk for listeriosis, but symptoms are non-specific and diagnosis is difficult. The intracellular life-cycle of Listeria protects the bacterium from host innate and adaptive immune responses. Antibiotic treatment requires agents able to penetrate, distribute, and remain stable within host cells. Prolonged use of high-dose ampicillin can significantly improve neonatal outcome.

Original languageEnglish
Pages (from-to)227-236
Number of pages10
JournalJournal of Perinatal Medicine
Volume39
Issue number3
DOIs
StatePublished - May 2011
Externally publishedYes

Keywords

  • Epidemics
  • Foodborne
  • Infection
  • Listeria monocytogenes
  • Listeriosis
  • Neonate
  • Newborn
  • Pregnancy

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